Epigenetics and Neural Plasticity Laboratory

Who are we?

The Epigenetics and Neural Plasticity Laboratory is a research laboratory lead by Professor Anthony Hannan which operates within the Florey Institute of Neuroscience and Mental Health.

What are our aims?

We seek to use our knowledge of pathology, in the brain and other areas of the body, to develop new treatments for various diseases and disorders, including Huntington's disease.

What do we do?

Prof. Anthony Hannan, Dr Thibault Renoir and colleagues focus on understanding Huntington’s disease (HD), and trying to develop new treatments. His research group provided the first demonstration in any genetic model that environmental stimulation can be therapeutic. This has led to new insights into gene-environment interactions in various brain disorders, including Huntington’s disease, dementia, depression, schizophrenia and autism spectrum disorders. This research team at the Florey explores how genes and the environment combine via experience-dependent plasticity in the healthy and diseased brain, including HD. Our ongoing research includes a preclinical model of HD investigated at behavioural, cellular and molecular levels so as to identify pathogenic mechanisms and novel therapeutic targets.

How can you find out more about our Huntington’s disease research and how we are trying to find ways to prevent and treat HD?

Visit our website!