Neuroinflammation in Huntington's Disease

In Huntington’s disease, the immune system of the brain is constantly trying to attack and remove the mutant huntingtin protein. But over time, this immune response called neuroinflammation can also become toxic to healthy brain cells!

Understanding and measuring neuroinflammation will help us to work out how much this immune response contributes to the progression of HD, and how we may be able to stop it.

How am I investigating inflammation?

This project uses combined Magnetic Resonance Imaging (MRI) and Positron Emission Tomography (PET) brain scanning, as well as blood tests and genetic analysis.

What will we learn from this research?

Your participation will contribute to our growing understanding of how the brain changes in HD, including new insights into how we may be able to track or treat this disorder in the future.

This study is not currently recruiting participants.

Ethics Approval: Monash University Research Ethics Committee (MUHREC) 2017-7810.

About HRGV

HRGV aims to advance knowledge about the cause(s), pathogenesis, clinical and social impacts of Huntington’s disease and related disorders and to develop and implement scientific strategies promising therapeutic and psychosocial interventions.

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Participants Required

We require participants for our numerous studies. Most studies offer some form of compensation for your time. Please take some time to look at our available studies here and help us improve treatment outcomes for people with Huntington's Disease. You can also sign up for our Participant Registry and be kept up to date with research projects that are relevant to you!

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